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Unknown  |  1992-06-06  |  334.8 KB

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ConfidenceProgramDetectionMatch TypeSupport
66% dexvert OS/2 Installation Package (archive/os2InstallPackage) ext Supported
1% dexvert BeOS Installation Package (archive/beOSInstallPackage) ext Unsupported
1% dexvert Newton Package (archive/newtonPackage) ext Unsupported
1% dexvert Independence War 2 mod Package (other/independenceWar2ModPackage) ext Unsupported
100% file data default



hex view
+--------+-------------------------+-------------------------+--------+--------+
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|00002c70| 33 39 20 63 6f 6e 74 61 | 63 74 73 2c 20 33 35 20 |39 conta|cts, 35 |
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|00002e00| 20 6f 66 20 74 68 65 20 | 33 39 20 68 65 74 65 72 | of the |39 heter|
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|00002e20| 20 77 61 73 20 24 34 31 | 2c 32 30 30 2e 0d 0a 20 | was $41|,200... |
|00002e30| 20 20 20 20 4f 66 20 74 | 68 65 20 33 39 20 73 6f | Of t|he 39 so|
|00002e40| 75 72 63 65 20 63 61 73 | 65 73 2c 20 33 32 20 28 |urce cas|es, 32 (|
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|00002e60| 20 61 6e 64 20 33 34 20 | 77 65 72 65 20 77 68 69 | and 34 |were whi|
|00002e70| 74 65 2e 20 20 41 66 74 | 65 72 0d 0a 65 78 63 6c |te. Aft|er..excl|
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|00002ee0| 20 61 67 72 65 65 64 20 | 74 6f 20 62 65 20 74 65 | agreed |to be te|
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|00002f00| 66 20 74 68 65 73 65 2c | 20 36 20 77 6f 6d 65 6e |f these,| 6 women|
|00002f10| 0d 0a 61 6e 64 20 31 20 | 6d 61 6e 20 77 65 72 65 |..and 1 |man were|
|00002f20| 20 73 65 72 6f 70 6f 73 | 69 74 69 76 65 20 66 6f | seropos|itive fo|
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|00002f50| 6e 74 61 63 74 73 20 6f | 66 20 61 0d 0a 70 61 74 |ntacts o|f a..pat|
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|000030a0| 20 70 6f 6f 72 20 6d 69 | 6e 6f 72 69 74 69 65 73 | poor mi|norities|
|000030b0| 2e 0d 0a 0d 0a 50 6f 73 | 74 2d 43 6f 6d 6d 65 6e |.....Pos|t-Commen|
|000030c0| 74 0d 0a 0d 0a 20 20 20 | 20 20 43 6c 65 61 72 6c |t.... | Clearl|
|000030d0| 79 2c 20 41 49 44 53 20 | 63 61 6e 20 6e 6f 20 6c |y, AIDS |can no l|
|000030e0| 6f 6e 67 65 72 20 62 65 | 20 63 6f 6e 73 69 64 65 |onger be| conside|
|000030f0| 72 65 64 20 74 68 65 20 | 65 78 63 6c 75 73 69 76 |red the |exclusiv|
|00003100| 65 20 64 69 73 65 61 73 | 65 20 6f 66 0d 0a 68 6f |e diseas|e of..ho|
|00003110| 6d 6f 73 65 78 75 61 6c | 20 70 61 74 69 65 6e 74 |mosexual| patient|
|00003120| 73 2e 20 20 52 65 63 65 | 6e 74 20 65 76 69 64 65 |s. Rece|nt evide|
|00003130| 6e 63 65 20 61 6c 73 6f | 20 73 75 67 67 65 73 74 |nce also| suggest|
|00003140| 73 20 74 68 61 74 20 74 | 68 65 20 64 69 73 65 61 |s that t|he disea|
|00003150| 73 65 20 63 61 6e 20 62 | 65 0d 0a 74 72 61 6e 73 |se can b|e..trans|
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|00003190| 74 6f 20 62 65 20 64 6f | 6e 65 20 74 6f 20 63 6c |to be do|ne to cl|
|000031a0| 61 72 69 66 79 20 74 68 | 65 0d 0a 72 69 73 6b 20 |arify th|e..risk |
|000031b0| 69 6e 76 6f 6c 76 65 64 | 20 69 6e 20 6f 72 61 6c |involved| in oral|
|000031c0| 20 74 72 61 6e 73 6d 69 | 73 73 69 6f 6e 2e 20 20 | transmi|ssion. |
|000031d0| 50 61 74 69 65 6e 74 73 | 20 61 74 20 72 69 73 6b |Patients| at risk|
|000031e0| 20 66 6f 72 20 61 63 71 | 75 69 72 69 6e 67 20 41 | for acq|uiring A|
|000031f0| 49 44 53 2c 0d 0a 68 6f | 77 65 76 65 72 2c 20 73 |IDS,..ho|wever, s|
|00003200| 68 6f 75 6c 64 20 62 65 | 20 61 64 76 69 73 65 64 |hould be| advised|
|00003210| 20 74 68 61 74 20 69 6e | 69 74 69 61 6c 20 72 65 | that in|itial re|
|00003220| 70 6f 72 74 73 20 74 68 | 61 74 20 74 68 65 20 76 |ports th|at the v|
|00003230| 69 72 75 73 20 63 61 6e | 6e 6f 74 20 62 65 0d 0a |irus can|not be..|
|00003240| 74 72 61 6e 73 6d 69 74 | 74 65 64 20 62 79 20 74 |transmit|ted by t|
|00003250| 68 65 20 6f 72 61 6c 20 | 72 6f 75 74 65 20 6d 61 |he oral |route ma|
|00003260| 79 20 6e 65 65 64 20 74 | 6f 20 62 65 20 72 65 74 |y need t|o be ret|
|00003270| 72 61 63 74 65 64 20 61 | 73 20 6d 6f 72 65 20 64 |racted a|s more d|
|00003280| 61 74 61 20 62 65 63 6f | 6d 65 0d 0a 61 76 61 69 |ata beco|me..avai|
|00003290| 6c 61 62 6c 65 2e 20 20 | 41 73 20 6e 6f 74 65 64 |lable. |As noted|
|000032a0| 20 62 79 20 46 69 73 63 | 68 6c 20 65 74 20 61 6c | by Fisc|hl et al|
|000032b0| 2e 20 28 73 65 65 20 74 | 68 65 20 31 39 38 38 20 |. (see t|he 1988 |
|000032c0| 59 45 41 52 20 42 4f 4f | 4b 20 4f 46 20 46 41 4d |YEAR BOO|K OF FAM|
|000032d0| 49 4c 59 0d 0a 50 52 41 | 43 54 49 43 45 2c 20 70 |ILY..PRA|CTICE, p|
|000032e0| 70 20 33 30 2d 33 31 29 | 2c 20 62 61 72 72 69 65 |p 30-31)|, barrie|
|000032f0| 72 20 70 72 6f 74 65 63 | 74 69 6f 6e 20 72 65 73 |r protec|tion res|
|00003300| 75 6c 74 65 64 20 69 6e | 20 31 20 6f 66 20 31 30 |ulted in| 1 of 10|
|00003310| 20 73 65 72 6f 63 6f 6e | 76 65 72 73 69 6f 6e 73 | serocon|versions|
|00003320| 0d 0a 63 6f 6d 70 61 72 | 65 64 20 77 69 74 68 20 |..compar|ed with |
|00003330| 31 32 20 6f 66 20 31 34 | 20 69 6e 20 70 65 72 73 |12 of 14| in pers|
|00003340| 6f 6e 73 20 77 68 6f 20 | 72 65 70 6f 72 74 65 64 |ons who |reported|
|00003350| 20 73 65 78 75 61 6c 20 | 63 6f 6e 74 61 63 74 20 | sexual |contact |
|00003360| 77 69 74 68 20 61 6e 20 | 69 6e 66 65 63 74 65 64 |with an |infected|
|00003370| 0d 0a 70 65 72 73 6f 6e | 20 77 69 74 68 6f 75 74 |..person| without|
|00003380| 20 75 73 65 20 6f 66 20 | 61 20 63 6f 6e 64 6f 6d | use of |a condom|
|00003390| 2e 2d 2d 43 2e 57 2e 20 | 53 6d 69 74 68 2c 20 4a |.--C.W. |Smith, J|
|000033a0| 72 2e 2c 20 4d 2e 44 2e | 0d 0a 24 55 6e 69 71 75 |r., M.D.|..$Uniqu|
|000033b0| 65 5f 49 44 7b 59 52 42 | 31 30 35 30 33 7d 0d 0a |e_ID{YRB|10503}..|
|000033c0| 24 54 69 74 6c 65 7b 4d | 6f 74 68 65 72 2d 54 6f |$Title{M|other-To|
|000033d0| 2d 43 68 69 6c 64 20 54 | 72 61 6e 73 6d 69 73 73 |-Child T|ransmiss|
|000033e0| 69 6f 6e 20 6f 66 20 48 | 49 56 20 49 6e 66 65 63 |ion of H|IV Infec|
|000033f0| 74 69 6f 6e 7d 0d 0a 24 | 41 75 74 68 6f 72 7b 45 |tion}..$|Author{E|
|00003400| 75 72 6f 70 65 61 6e 20 | 43 6f 6c 6c 61 62 6f 72 |uropean |Collabor|
|00003410| 61 74 69 76 65 20 53 74 | 75 64 79 7d 0d 0a 24 41 |ative St|udy}..$A|
|00003420| 66 66 69 6c 69 61 74 69 | 6f 6e 7b 49 6e 73 74 20 |ffiliati|on{Inst |
|00003430| 6f 66 20 43 68 69 6c 64 | 20 48 65 61 6c 74 68 2c |of Child| Health,|
|00003440| 20 4c 6f 6e 64 6f 6e 7d | 0d 0a 24 4a 6f 75 72 6e | London}|..$Journ|
|00003450| 61 6c 7b 4c 61 6e 63 65 | 74 7d 0d 0a 24 56 6f 6c |al{Lance|t}..$Vol|
|00003460| 75 6d 65 7b 32 7d 0d 0a | 24 50 61 67 65 7b 31 30 |ume{2}..|$Page{10|
|00003470| 33 39 2d 31 30 34 33 7d | 0d 0a 24 44 61 74 65 7b |39-1043}|..$Date{|
|00003480| 4e 6f 76 20 35 2c 20 31 | 39 38 38 7d 0d 0a 24 59 |Nov 5, 1|988}..$Y|
|00003490| 42 56 6f 6c 7b 31 39 39 | 30 20 59 65 61 72 20 42 |BVol{199|0 Year B|
|000034a0| 6f 6f 6b 20 6f 66 20 46 | 61 6d 69 6c 79 20 50 72 |ook of F|amily Pr|
|000034b0| 61 63 74 69 63 65 7d 0d | 0a 24 43 68 61 70 74 65 |actice}.|.$Chapte|
|000034c0| 72 7b 31 2d 34 7d 0d 0a | 24 59 42 45 64 69 74 6f |r{1-4}..|$YBEdito|
|000034d0| 72 7b 44 72 73 2e 20 52 | 61 6b 65 6c 2c 20 41 76 |r{Drs. R|akel, Av|
|000034e0| 61 6e 74 2c 20 44 72 69 | 73 63 6f 6c 6c 2c 20 50 |ant, Dri|scoll, P|
|000034f0| 72 69 63 68 61 72 64 2c | 20 61 6e 64 20 53 6d 69 |richard,| and Smi|
|00003500| 74 68 7d 0d 0a 24 54 61 | 62 6c 65 7b 7d 0d 0a 24 |th}..$Ta|ble{}..$|
|00003510| 43 6f 6d 6d 65 6e 74 61 | 74 6f 72 7b 43 2e 57 2e |Commenta|tor{C.W.|
|00003520| 20 53 6d 69 74 68 2c 20 | 4a 72 2e 2c 20 4d 2e 44 | Smith, |Jr., M.D|
|00003530| 2e 7d 0d 0a 0d 0a 43 6f | 70 79 72 69 67 68 74 20 |.}....Co|pyright |
|00003540| 28 63 29 20 59 65 61 72 | 62 6f 6f 6b 20 4d 65 64 |(c) Year|book Med|
|00003550| 69 63 61 6c 20 50 75 62 | 6c 69 73 68 65 72 73 2c |ical Pub|lishers,|
|00003560| 20 49 6e 63 2e 2c 20 31 | 39 39 30 0d 0a 0d 0a 31 | Inc., 1|990....1|
|00003570| 39 39 30 20 59 65 61 72 | 20 42 6f 6f 6b 20 6f 66 |990 Year| Book of|
|00003580| 20 46 61 6d 69 6c 79 20 | 50 72 61 63 74 69 63 65 | Family |Practice|
|00003590| 20 28 52 29 0d 0a 0d 0a | 43 68 61 70 74 65 72 20 | (R)....|Chapter |
|000035a0| 31 2d 2d 49 6e 66 65 63 | 74 69 6f 75 73 20 44 69 |1--Infec|tious Di|
|000035b0| 73 65 61 73 65 0d 0a 0d | 0a 2d 2d 2d 2d 2d 2d 2d |sease...|.-------|
|000035c0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000035d0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000035e0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000035f0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00003600| 2d 2d 2d 2d 2d 2d 2d 0d | 0a 4d 6f 74 68 65 72 2d |-------.|.Mother-|
|00003610| 54 6f 2d 43 68 69 6c 64 | 20 54 72 61 6e 73 6d 69 |To-Child| Transmi|
|00003620| 73 73 69 6f 6e 20 6f 66 | 20 48 49 56 20 49 6e 66 |ssion of| HIV Inf|
|00003630| 65 63 74 69 6f 6e 0d 0a | 0d 0a 45 75 72 6f 70 65 |ection..|..Europe|
|00003640| 61 6e 20 43 6f 6c 6c 61 | 62 6f 72 61 74 69 76 65 |an Colla|borative|
|00003650| 20 53 74 75 64 79 0d 0a | 28 49 6e 73 74 20 6f 66 | Study..|(Inst of|
|00003660| 20 43 68 69 6c 64 20 48 | 65 61 6c 74 68 2c 20 4c | Child H|ealth, L|
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|00003680| 3a 31 30 33 39 2d 31 30 | 34 33 2c 20 4e 6f 76 20 |:1039-10|43, Nov |
|00003690| 35 2c 20 31 39 38 38 0d | 0a 2d 2d 2d 2d 2d 2d 2d |5, 1988.|.-------|
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|000036d0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
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|00003d40| 0d 0a 0d 0a 50 6f 73 74 | 2d 43 6f 6d 6d 65 6e 74 |....Post|-Comment|
|00003d50| 0d 0a 0d 0a 20 20 20 20 | 20 54 68 61 74 20 6f 6e |.... | That on|
|00003d60| 6c 79 20 31 30 20 6f 66 | 20 32 37 31 20 63 68 69 |ly 10 of| 271 chi|
|00003d70| 6c 64 72 65 6e 20 62 6f | 72 6e 20 74 6f 20 6d 6f |ldren bo|rn to mo|
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|00003da0| 0d 0a 65 6e 63 6f 75 72 | 61 67 69 6e 67 2e 20 20 |..encour|aging. |
|00003db0| 48 6f 77 65 76 65 72 2c | 20 74 68 65 20 64 61 74 |However,| the dat|
|00003dc0| 61 20 67 69 76 65 20 74 | 68 65 20 63 6c 69 6e 69 |a give t|he clini|
|00003dd0| 63 69 61 6e 20 6e 6f 20 | 72 65 61 73 6f 6e 20 74 |cian no |reason t|
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|00003df0| 63 68 69 6c 64 72 65 6e | 20 77 69 74 68 20 74 68 |children| with th|
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|00003e30| 20 20 43 61 72 65 66 75 | 6c 0d 0a 65 66 66 6f 72 | Carefu|l..effor|
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|00003e50| 65 20 74 6f 20 70 72 65 | 76 65 6e 74 20 77 6f 6d |e to pre|vent wom|
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|00003e70| 69 6e 67 20 61 67 65 20 | 77 69 74 68 20 41 49 44 |ing age |with AID|
|00003e80| 53 20 66 72 6f 6d 0d 0a | 62 65 63 6f 6d 69 6e 67 |S from..|becoming|
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|00003ea0| 20 53 6d 69 74 68 2c 20 | 4a 72 2e 2c 20 4d 2e 44 | Smith, |Jr., M.D|
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|00003f10| 57 68 6f 20 52 65 6d 61 | 69 6e 20 53 65 72 6f 6e |Who Rema|in Seron|
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|00003f30| 6f 6e 67 65 64 20 50 65 | 72 69 6f 64 73 7d 0d 0a |onged Pe|riods}..|
|00003f40| 24 41 75 74 68 6f 72 7b | 49 6d 61 67 61 77 61 2c |$Author{|Imagawa,|
|00003f50| 20 44 54 0d 0a 4c 65 65 | 2c 20 4d 48 0d 0a 57 6f | DT..Lee|, MH..Wo|
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|00003f90| 79 2c 20 4a 4a 0d 0a 4e | 69 73 68 61 6e 69 61 6e |y, JJ..N|ishanian|
|00003fa0| 2c 20 50 47 0d 0a 47 69 | 6f 72 67 69 2c 20 4a 0d |, PG..Gi|orgi, J.|
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|00003fc0| 65 79 2c 20 4a 0d 0a 56 | 69 73 73 63 68 65 72 2c |ey, J..V|isscher,|
|00003fd0| 20 42 52 0d 0a 44 65 74 | 65 6c 73 2c 20 52 7d 0d | BR..Det|els, R}.|
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|000040f0| 50 72 69 63 68 61 72 64 | 2c 20 61 6e 64 20 53 6d |Prichard|, and Sm|
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|00004130| 2c 20 4d 2e 48 53 7d 0d | 0a 0d 0a 43 6f 70 79 72 |, M.HS}.|...Copyr|
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|00004190| 63 74 69 63 65 20 28 52 | 29 0d 0a 0d 0a 43 68 61 |ctice (R|)....Cha|
|000041a0| 70 74 65 72 20 31 2d 2d | 49 6e 66 65 63 74 69 6f |pter 1--|Infectio|
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|00004210| 6d 61 6e 20 49 6d 6d 75 | 6e 6f 64 65 66 69 63 69 |man Immu|nodefici|
|00004220| 65 6e 63 79 20 56 69 72 | 75 73 20 54 79 70 65 20 |ency Vir|us Type |
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|00004280| 49 6d 61 67 61 77 61 20 | 44 54 3b 20 4c 65 65 20 |Imagawa |DT; Lee |
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|00004340| 20 43 65 74 75 73 20 43 | 6f 72 70 2c 20 45 6d 65 | Cetus C|orp, Eme|
|00004350| 72 79 76 69 6c 6c 65 2c | 0d 0a 43 61 6c 69 66 29 |ryville,|..Calif)|
|00004360| 0d 0a 4e 20 45 6e 67 6c | 20 4a 20 4d 65 64 20 33 |..N Engl| J Med 3|
|00004370| 32 30 3a 31 34 35 38 2d | 31 34 36 32 2c 20 4a 75 |20:1458-|1462, Ju|
|00004380| 6e 65 20 31 2c 20 31 39 | 38 39 0d 0a 2d 2d 2d 2d |ne 1, 19|89..----|
|00004390| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000043a0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000043b0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000043c0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|000043d0| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 0d 0a 0d 0a 41 62 |--------|--....Ab|
|000043e0| 73 74 72 61 63 74 0d 0a | 0d 0a 20 20 20 20 20 53 |stract..|.. S|
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|00004480| 0a 65 6e 7a 79 6d 61 74 | 69 63 20 61 6d 70 6c 69 |.enzymat|ic ampli|
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|00004500| 6c 76 65 64 20 69 6e 20 | 68 69 67 68 2d 72 69 73 |lved in |high-ris|
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|000045c0| 6f 6f 64 20 6c 79 6d 70 | 68 6f 63 79 74 65 73 20 |ood lymp|hocytes |
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|000045e0| 69 74 68 20 6d 69 74 6f | 67 65 6e 20 73 74 69 6d |ith mito|gen stim|
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|00004610| 74 65 67 72 61 74 65 64 | 20 48 49 56 2d 31 20 67 |tegrated| HIV-1 g|
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|00004640| 49 56 2d 31 20 69 6e 20 | 73 61 6d 70 6c 65 73 20 |IV-1 in |samples |
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|00004690| 20 61 66 74 65 72 20 62 | 65 69 6e 67 20 6e 65 67 | after b|eing neg|
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|000046c0| 65 72 20 32 37 20 72 65 | 6d 61 69 6e 65 64 20 73 |er 27 re|mained s|
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|000046e0| 38 2d 33 36 20 6d 6f 6e | 74 68 73 2e 20 20 56 69 |8-36 mon|ths. Vi|
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|00004760| 61 6c 74 68 6f 75 67 68 | 20 73 65 72 6f 63 6f 6e |although| serocon|
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|00004790| 6f 74 68 65 72 20 33 30 | 20 6d 6f 6e 74 68 73 2e |other 30| months.|
|000047a0| 20 20 49 6e 20 74 68 65 | 20 34 20 6d 65 6e 20 77 | In the| 4 men w|
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|000047c0| 20 64 75 72 69 6e 67 20 | 74 68 65 20 73 74 75 64 | during |the stud|
|000047d0| 79 2c 20 74 68 65 20 6c | 65 76 65 6c 0d 0a 6f 66 |y, the l|evel..of|
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|00004870| 69 6f 6e 2c 0d 0a 73 75 | 67 67 65 73 74 69 6e 67 |ion,..su|ggesting|
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|000048a0| 72 65 6c 65 61 73 65 20 | 6f 66 20 76 69 72 61 6c |release |of viral|
|000048b0| 20 61 6e 74 69 67 65 6e | 73 20 61 72 65 20 6e 65 | antigen|s are ne|
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|000048d0| 6e 76 65 72 73 69 6f 6e | 2e 0d 0a 20 20 20 20 20 |nversion|... |
|000048e0| 41 70 70 61 72 65 6e 74 | 6c 79 2c 20 61 20 73 69 |Apparent|ly, a si|
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|00004910| 72 20 69 6e 20 68 6f 6d | 6f 73 65 78 75 61 6c 20 |r in hom|osexual |
|00004920| 6d 65 6e 20 77 69 74 68 | 0d 0a 48 49 56 20 69 6e |men with|..HIV in|
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|00004950| 20 6d 61 79 20 6e 6f 74 | 20 62 65 20 61 63 74 69 | may not| be acti|
|00004960| 76 61 74 65 64 20 62 79 | 20 73 74 69 6d 75 6c 69 |vated by| stimuli|
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|000049a0| 20 73 6f 6f 6e 65 72 2d | 2d 77 69 74 68 69 6e 20 | sooner-|-within |
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|000049c0| 72 0d 0a 64 69 72 65 63 | 74 20 62 6c 6f 6f 64 73 |r..direc|t bloods|
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|00004a40| 74 20 73 65 72 6f 63 6f | 6e 76 65 72 74 65 64 20 |t seroco|nverted |
|00004a50| 63 61 6e 20 74 72 61 6e | 73 6d 69 74 20 74 68 65 |can tran|smit the|
|00004a60| 0d 0a 69 6e 66 65 63 74 | 69 6f 6e 2c 20 6f 72 20 |..infect|ion, or |
|00004a70| 77 68 65 74 68 65 72 20 | 73 6f 6d 65 20 70 65 72 |whether |some per|
|00004a80| 73 6f 6e 73 20 6d 61 79 | 20 68 61 72 62 6f 72 20 |sons may| harbor |
|00004a90| 74 68 65 20 76 69 72 75 | 73 20 62 75 74 20 6e 65 |the viru|s but ne|
|00004aa0| 76 65 72 20 73 65 72 6f | 63 6f 6e 76 65 72 74 2e |ver sero|convert.|
|00004ab0| 0d 0a 0d 0a 50 6f 73 74 | 2d 43 6f 6d 6d 65 6e 74 |....Post|-Comment|
|00004ac0| 0d 0a 0d 0a 20 20 20 20 | 20 54 68 69 73 20 69 6d |.... | This im|
|00004ad0| 70 6f 72 74 61 6e 74 20 | 73 74 75 64 79 20 64 65 |portant |study de|
|00004ae0| 6d 6f 6e 73 74 72 61 74 | 65 73 20 74 68 61 74 20 |monstrat|es that |
|00004af0| 69 6e 20 73 6f 6d 65 20 | 69 6e 64 69 76 69 64 75 |in some |individu|
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|00004b10| 0a 48 49 56 20 6d 61 79 | 20 6e 6f 74 20 62 65 20 |.HIV may| not be |
|00004b20| 70 72 6f 64 75 63 65 64 | 20 66 6f 72 20 6d 6f 72 |produced| for mor|
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|00004b40| 74 65 72 20 69 6e 66 65 | 63 74 69 6f 6e 2e 20 20 |ter infe|ction. |
|00004b50| 54 68 65 20 64 69 66 66 | 69 63 75 6c 74 79 0d 0a |The diff|iculty..|
|00004b60| 69 73 20 74 68 61 74 20 | 6d 6f 73 74 20 73 65 72 |is that |most ser|
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|00004b80| 74 75 64 69 65 73 20 61 | 72 65 20 62 61 73 65 64 |tudies a|re based|
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|00004bc0| 6c 61 74 74 65 72 20 74 | 65 73 74 20 68 61 73 20 |latter t|est has |
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|00004c40| 6e 63 69 64 65 6e 63 65 | 20 6f 66 20 69 6e 66 65 |ncidence| of infe|
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|00004c60| 69 6f 75 73 20 70 6f 70 | 75 6c 61 74 69 6f 6e 73 |ious pop|ulations|
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|00004c80| 76 65 20 6d 65 74 68 6f | 64 73 20 6f 66 0d 0a 64 |ve metho|ds of..d|
|00004c90| 65 74 65 63 74 69 6e 67 | 20 76 69 72 61 6c 20 44 |etecting| viral D|
|00004ca0| 4e 41 2c 20 74 68 65 20 | 61 75 74 68 6f 72 73 20 |NA, the |authors |
|00004cb0| 77 65 72 65 20 61 62 6c | 65 20 74 6f 20 64 65 6d |were abl|e to dem|
|00004cc0| 6f 6e 73 74 72 61 74 65 | 20 74 68 61 74 20 48 49 |onstrate| that HI|
|00004cd0| 56 20 69 6e 66 65 63 74 | 69 6f 6e 0d 0a 6f 63 63 |V infect|ion..occ|
|00004ce0| 75 72 72 65 64 20 61 73 | 20 6c 6f 6e 67 20 61 73 |urred as| long as|
|00004cf0| 20 33 35 20 6d 6f 6e 74 | 68 73 20 62 65 66 6f 72 | 35 mont|hs befor|
|00004d00| 65 20 73 65 72 6f 63 6f | 6e 76 65 72 73 69 6f 6e |e seroco|nversion|
|00004d10| 2e 20 20 48 65 6e 63 65 | 2c 20 64 65 73 70 69 74 |. Hence|, despit|
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|00004d30| 69 6f 6e 2c 20 74 65 73 | 74 73 20 62 61 73 65 64 |ion, tes|ts based|
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|00004d50| 74 69 62 6f 64 79 20 77 | 6f 75 6c 64 20 67 69 76 |tibody w|ould giv|
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|00004d70| 76 65 0d 0a 72 65 73 75 | 6c 74 73 2e 0d 0a 20 20 |ve..resu|lts... |
|00004d80| 20 20 20 47 69 76 65 6e | 20 74 68 65 20 62 69 6f | Given| the bio|
|00004d90| 6c 6f 67 79 20 6f 66 20 | 72 65 74 72 6f 76 69 72 |logy of |retrovir|
|00004da0| 75 73 65 73 20 69 74 20 | 69 73 20 70 65 72 68 61 |uses it |is perha|
|00004db0| 70 73 20 6e 6f 74 20 73 | 75 72 70 72 69 73 69 6e |ps not s|urprisin|
|00004dc0| 67 20 74 68 61 74 0d 0a | 69 6e 66 65 63 74 69 6f |g that..|infectio|
|00004dd0| 6e 20 63 61 6e 20 6f 63 | 63 75 72 20 77 69 74 68 |n can oc|cur with|
|00004de0| 6f 75 74 20 73 65 72 6f | 6c 6f 67 69 63 20 65 76 |out sero|logic ev|
|00004df0| 69 64 65 6e 63 65 20 74 | 68 65 72 65 6f 66 2e 20 |idence t|hereof. |
|00004e00| 20 54 68 65 20 66 72 65 | 71 75 65 6e 63 79 20 77 | The fre|quency w|
|00004e10| 69 74 68 0d 0a 77 68 69 | 63 68 20 69 6e 66 65 63 |ith..whi|ch infec|
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|00004e30| 6f 77 65 64 20 62 79 20 | 61 6e 74 69 62 6f 64 79 |owed by |antibody|
|00004e40| 20 70 72 6f 64 75 63 74 | 69 6f 6e 20 68 61 73 20 | product|ion has |
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|00004f20| 20 75 6e 6b 6e 6f 77 6e | 2e 2d 2d 4a 2e 47 2e 0d | unknown|.--J.G..|
|00004f30| 0a 50 72 69 63 68 61 72 | 64 2c 20 4d 2e 44 2e 2c |.Prichar|d, M.D.,|
|00004f40| 20 4d 2e 48 53 0d 0a 24 | 55 6e 69 71 75 65 5f 49 | M.HS..$|Unique_I|
|00004f50| 44 7b 59 52 42 31 30 35 | 30 35 7d 0d 0a 24 54 69 |D{YRB105|05}..$Ti|
|00004f60| 74 6c 65 7b 49 6e 63 69 | 64 65 6e 63 65 20 6f 66 |tle{Inci|dence of|
|00004f70| 20 53 79 6d 70 74 6f 6d | 73 20 61 6e 64 20 41 49 | Symptom|s and AI|
|00004f80| 44 53 20 69 6e 20 31 34 | 36 20 53 77 65 64 69 73 |DS in 14|6 Swedis|
|00004f90| 68 20 48 61 65 6d 6f 70 | 68 69 6c 69 61 63 73 20 |h Haemop|hiliacs |
|00004fa0| 61 6e 64 20 42 6c 6f 6f | 64 20 54 72 61 6e 73 66 |and Bloo|d Transf|
|00004fb0| 75 73 69 6f 6e 20 52 65 | 63 69 70 69 65 6e 74 73 |usion Re|cipients|
|00004fc0| 20 49 6e 66 65 63 74 65 | 64 20 57 69 74 68 20 48 | Infecte|d With H|
|00004fd0| 75 6d 61 6e 20 49 6d 6d | 75 6e 6f 64 65 66 69 63 |uman Imm|unodefic|
|00004fe0| 69 65 6e 63 79 20 56 69 | 72 75 73 7d 0d 0a 24 41 |iency Vi|rus}..$A|
|00004ff0| 75 74 68 6f 72 7b 47 69 | 65 73 65 63 6b 65 2c 20 |uthor{Gi|esecke, |
|00005000| 4a 0d 0a 53 63 61 6c 69 | 61 2d 54 6f 6d 62 61 2c |J..Scali|a-Tomba,|
|00005010| 20 47 0d 0a 42 65 72 67 | 6c 75 6e 64 2c 20 4f 0d | G..Berg|lund, O.|
|00005020| 0a 42 65 72 6e 74 6f 72 | 70 2c 20 45 0d 0a 53 63 |.Berntor|p, E..Sc|
|00005030| 68 75 6c 6d 61 6e 2c 20 | 53 0d 0a 53 74 69 67 65 |hulman, |S..Stige|
|00005040| 6e 64 61 6c 2c 20 4c 7d | 0d 0a 24 41 66 66 69 6c |ndal, L}|..$Affil|
|00005050| 69 61 74 69 6f 6e 7b 4b | 61 72 6f 6c 69 6e 73 6b |iation{K|arolinsk|
|00005060| 61 20 48 6f 73 70 2c 20 | 53 74 6f 63 6b 68 6f 6c |a Hosp, |Stockhol|
|00005070| 6d 3b 20 52 6f 73 6c 61 | 67 73 74 75 6c 6c 20 48 |m; Rosla|gstull H|
|00005080| 6f 73 70 2c 20 53 74 6f | 63 6b 68 6f 6c 6d 3b 20 |osp, Sto|ckholm; |
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|000050a0| 6c 6d 6f 2c 20 53 77 65 | 64 65 6e 3b 20 55 6e 69 |lmo, Swe|den; Uni|
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|000050c0| 0d 0a 24 4a 6f 75 72 6e | 61 6c 7b 42 72 20 4d 65 |..$Journ|al{Br Me|
|000050d0| 64 20 4a 7d 0d 0a 24 56 | 6f 6c 75 6d 65 7b 32 39 |d J}..$V|olume{29|
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|00005110| 39 39 30 20 59 65 61 72 | 20 42 6f 6f 6b 20 6f 66 |990 Year| Book of|
|00005120| 20 46 61 6d 69 6c 79 20 | 50 72 61 63 74 69 63 65 | Family |Practice|
|00005130| 7d 0d 0a 24 43 68 61 70 | 74 65 72 7b 31 2d 36 7d |}..$Chap|ter{1-6}|
|00005140| 0d 0a 24 59 42 45 64 69 | 74 6f 72 7b 44 72 73 2e |..$YBEdi|tor{Drs.|
|00005150| 20 52 61 6b 65 6c 2c 20 | 41 76 61 6e 74 2c 20 44 | Rakel, |Avant, D|
|00005160| 72 69 73 63 6f 6c 6c 2c | 20 50 72 69 63 68 61 72 |riscoll,| Prichar|
|00005170| 64 2c 20 61 6e 64 20 53 | 6d 69 74 68 7d 0d 0a 24 |d, and S|mith}..$|
|00005180| 54 61 62 6c 65 7b 54 61 | 62 6c 65 20 4f 6d 69 74 |Table{Ta|ble Omit|
|00005190| 74 65 64 7d 0d 0a 24 43 | 6f 6d 6d 65 6e 74 61 74 |ted}..$C|ommentat|
|000051a0| 6f 72 7b 4a 2e 47 2e 20 | 50 72 69 63 68 61 72 64 |or{J.G. |Prichard|
|000051b0| 2c 20 4d 2e 44 2e 2c 20 | 4d 2e 48 53 7d 0d 0a 0d |, M.D., |M.HS}...|
|000051c0| 0a 43 6f 70 79 72 69 67 | 68 74 20 28 63 29 20 59 |.Copyrig|ht (c) Y|
|000051d0| 65 61 72 62 6f 6f 6b 20 | 4d 65 64 69 63 61 6c 20 |earbook |Medical |
|000051e0| 50 75 62 6c 69 73 68 65 | 72 73 2c 20 49 6e 63 2e |Publishe|rs, Inc.|
|000051f0| 2c 20 31 39 39 30 0d 0a | 0d 0a 31 39 39 30 20 59 |, 1990..|..1990 Y|
|00005200| 65 61 72 20 42 6f 6f 6b | 20 6f 66 20 46 61 6d 69 |ear Book| of Fami|
|00005210| 6c 79 20 50 72 61 63 74 | 69 63 65 20 28 52 29 0d |ly Pract|ice (R).|
|00005220| 0a 0d 0a 43 68 61 70 74 | 65 72 20 31 2d 2d 49 6e |...Chapt|er 1--In|
|00005230| 66 65 63 74 69 6f 75 73 | 20 44 69 73 65 61 73 65 |fectious| Disease|
|00005240| 0d 0a 0d 0a 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |....----|--------|
|00005250| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005260| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005270| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005280| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005290| 2d 2d 0d 0a 49 6e 63 69 | 64 65 6e 63 65 20 6f 66 |--..Inci|dence of|
|000052a0| 20 53 79 6d 70 74 6f 6d | 73 20 61 6e 64 20 41 49 | Symptom|s and AI|
|000052b0| 44 53 20 69 6e 20 31 34 | 36 20 53 77 65 64 69 73 |DS in 14|6 Swedis|
|000052c0| 68 20 48 61 65 6d 6f 70 | 68 69 6c 69 61 63 73 20 |h Haemop|hiliacs |
|000052d0| 61 6e 64 20 42 6c 6f 6f | 64 0d 0a 54 72 61 6e 73 |and Bloo|d..Trans|
|000052e0| 66 75 73 69 6f 6e 20 52 | 65 63 69 70 69 65 6e 74 |fusion R|ecipient|
|000052f0| 73 20 49 6e 66 65 63 74 | 65 64 20 57 69 74 68 20 |s Infect|ed With |
|00005300| 48 75 6d 61 6e 20 49 6d | 6d 75 6e 6f 64 65 66 69 |Human Im|munodefi|
|00005310| 63 69 65 6e 63 79 20 56 | 69 72 75 73 0d 0a 0d 0a |ciency V|irus....|
|00005320| 47 69 65 73 65 63 6b 65 | 20 4a 3b 20 53 63 61 6c |Giesecke| J; Scal|
|00005330| 69 61 2d 54 6f 6d 62 61 | 20 47 3b 20 42 65 72 67 |ia-Tomba| G; Berg|
|00005340| 6c 75 6e 64 20 4f 3b 20 | 42 65 72 6e 74 6f 72 70 |lund O; |Berntorp|
|00005350| 20 45 3b 20 53 63 68 75 | 6c 6d 61 6e 20 53 3b 20 | E; Schu|lman S; |
|00005360| 53 74 69 67 65 6e 64 61 | 6c 20 4c 0d 0a 28 4b 61 |Stigenda|l L..(Ka|
|00005370| 72 6f 6c 69 6e 73 6b 61 | 20 48 6f 73 70 2c 20 53 |rolinska| Hosp, S|
|00005380| 74 6f 63 6b 68 6f 6c 6d | 3b 20 52 6f 73 6c 61 67 |tockholm|; Roslag|
|00005390| 73 74 75 6c 6c 20 48 6f | 73 70 2c 20 53 74 6f 63 |stull Ho|sp, Stoc|
|000053a0| 6b 68 6f 6c 6d 3b 20 55 | 6e 69 76 20 6f 66 20 4c |kholm; U|niv of L|
|000053b0| 75 6e 64 2c 20 4d 61 6c | 6d 6f 2c 0d 0a 53 77 65 |und, Mal|mo,..Swe|
|000053c0| 64 65 6e 3b 20 55 6e 69 | 76 20 6f 66 20 47 6f 74 |den; Uni|v of Got|
|000053d0| 68 65 6e 62 75 72 67 29 | 0d 0a 42 72 20 4d 65 64 |henburg)|..Br Med|
|000053e0| 20 4a 20 32 39 37 3a 39 | 39 2d 31 30 32 2c 20 4a | J 297:9|9-102, J|
|000053f0| 75 6c 79 20 39 2c 20 31 | 39 38 38 0d 0a 2d 2d 2d |uly 9, 1|988..---|
|00005400| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005410| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005420| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005430| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005440| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 0d 0a 0d 0a 41 |--------|---....A|
|00005450| 62 73 74 72 61 63 74 0d | 0a 0d 0a 20 20 20 20 20 |bstract.|... |
|00005460| 54 68 65 20 64 65 76 65 | 6c 6f 70 6d 65 6e 74 20 |The deve|lopment |
|00005470| 6f 66 20 61 63 71 75 69 | 72 65 64 20 69 6d 6d 75 |of acqui|red immu|
|00005480| 6e 6f 64 65 66 69 63 69 | 65 6e 63 79 20 73 79 6e |nodefici|ency syn|
|00005490| 64 72 6f 6d 65 20 28 41 | 49 44 53 29 20 77 61 73 |drome (A|IDS) was|
|000054a0| 0d 0a 69 6e 76 65 73 74 | 69 67 61 74 65 64 20 69 |..invest|igated i|
|000054b0| 6e 20 61 20 70 72 6f 73 | 70 65 63 74 69 76 65 20 |n a pros|pective |
|000054c0| 73 65 72 69 65 73 20 6f | 66 20 39 38 20 68 65 6d |series o|f 98 hem|
|000054d0| 6f 70 68 69 6c 69 61 63 | 73 20 61 6e 64 20 34 38 |ophiliac|s and 48|
|000054e0| 20 62 6c 6f 6f 64 0d 0a | 72 65 63 69 70 69 65 6e | blood..|recipien|
|000054f0| 74 73 20 69 6e 66 65 63 | 74 65 64 20 77 69 74 68 |ts infec|ted with|
|00005500| 20 68 75 6d 61 6e 20 69 | 6d 6d 75 6e 6f 64 65 66 | human i|mmunodef|
|00005510| 69 63 69 65 6e 63 79 20 | 76 69 72 75 73 20 28 48 |iciency |virus (H|
|00005520| 49 56 29 2e 20 20 54 68 | 65 20 6d 65 64 69 61 6e |IV). Th|e median|
|00005530| 0d 0a 66 6f 6c 6c 6f 77 | 2d 75 70 20 61 66 74 65 |..follow|-up afte|
|00005540| 72 20 69 6e 66 65 63 74 | 69 6f 6e 20 77 61 73 20 |r infect|ion was |
|00005550| 36 31 20 6d 6f 6e 74 68 | 73 2c 20 6f 72 20 37 30 |61 month|s, or 70|
|00005560| 20 6d 6f 6e 74 68 73 20 | 66 6f 72 20 74 68 65 20 | months |for the |
|00005570| 68 65 6d 6f 70 68 69 6c | 69 61 63 73 2e 0d 0a 53 |hemophil|iacs...S|
|00005580| 79 6d 70 74 6f 6d 73 20 | 64 65 76 65 6c 6f 70 65 |ymptoms |develope|
|00005590| 64 20 69 6e 20 33 39 20 | 68 65 6d 6f 70 68 69 6c |d in 39 |hemophil|
|000055a0| 69 61 63 73 2c 20 37 20 | 6f 66 20 77 68 6f 6d 20 |iacs, 7 |of whom |
|000055b0| 70 72 6f 67 72 65 73 73 | 65 64 20 74 6f 20 41 49 |progress|ed to AI|
|000055c0| 44 53 2e 20 20 4f 66 20 | 31 36 0d 0a 74 72 61 6e |DS. Of |16..tran|
|000055d0| 73 66 75 73 69 6f 6e 20 | 72 65 63 69 70 69 65 6e |sfusion |recipien|
|000055e0| 74 73 20 77 69 74 68 20 | 73 79 6d 70 74 6f 6d 73 |ts with |symptoms|
|000055f0| 2c 20 31 30 20 68 61 64 | 20 41 49 44 53 2e 20 20 |, 10 had| AIDS. |
|00005600| 54 68 65 20 72 61 74 65 | 20 6f 66 20 70 72 6f 67 |The rate| of prog|
|00005610| 72 65 73 73 69 6f 6e 20 | 74 6f 0d 0a 41 49 44 53 |ression |to..AIDS|
|00005620| 20 77 61 73 20 67 72 65 | 61 74 65 72 20 69 6e 20 | was gre|ater in |
|00005630| 74 68 65 20 74 72 61 6e | 73 66 75 73 69 6f 6e 20 |the tran|sfusion |
|00005640| 72 65 63 69 70 69 65 6e | 74 73 20 28 46 69 67 73 |recipien|ts (Figs|
|00005650| 20 31 2d 31 20 61 6e 64 | 20 31 2d 32 29 2c 20 61 | 1-1 and| 1-2), a|
|00005660| 6e 64 20 74 68 65 0d 0a | 64 69 66 66 65 72 65 6e |nd the..|differen|
|00005670| 63 65 20 69 6e 20 74 69 | 6d 65 20 74 6f 20 69 6e |ce in ti|me to in|
|00005680| 69 74 69 61 6c 20 73 79 | 6d 70 74 6f 6d 73 20 77 |itial sy|mptoms w|
|00005690| 61 73 20 6c 65 73 73 20 | 6d 61 72 6b 65 64 2e 0d |as less |marked..|
|000056a0| 0a 20 20 20 20 20 54 68 | 65 73 65 20 66 69 6e 64 |. Th|ese find|
|000056b0| 69 6e 67 73 20 73 75 67 | 67 65 73 74 20 74 68 61 |ings sug|gest tha|
|000056c0| 74 20 61 62 6f 75 74 20 | 68 61 6c 66 20 6f 66 20 |t about |half of |
|000056d0| 48 49 56 2d 70 6f 73 69 | 74 69 76 65 20 70 65 72 |HIV-posi|tive per|
|000056e0| 73 6f 6e 73 20 77 69 6c | 6c 0d 0a 65 78 70 65 72 |sons wil|l..exper|
|000056f0| 69 65 6e 63 65 20 63 6c | 69 6e 69 63 61 6c 20 73 |ience cl|inical s|
|00005700| 69 67 6e 73 20 6f 72 20 | 73 79 6d 70 74 6f 6d 73 |igns or |symptoms|
|00005710| 20 77 69 74 68 69 6e 20 | 35 2d 36 20 79 65 61 72 | within |5-6 year|
|00005720| 73 20 61 66 74 65 72 20 | 69 6e 66 65 63 74 69 6f |s after |infectio|
|00005730| 6e 2e 20 20 42 6f 74 68 | 0d 0a 73 79 6d 70 74 6f |n. Both|..sympto|
|00005740| 6d 73 20 61 6e 64 20 41 | 49 44 53 20 64 65 76 65 |ms and A|IDS deve|
|00005750| 6c 6f 70 20 6d 6f 72 65 | 20 72 61 70 69 64 6c 79 |lop more| rapidly|
|00005760| 20 69 6e 20 74 72 61 6e | 73 66 75 73 69 6f 6e 20 | in tran|sfusion |
|00005770| 72 65 63 69 70 69 65 6e | 74 73 20 74 68 61 6e 20 |recipien|ts than |
|00005780| 69 6e 0d 0a 68 65 6d 6f | 70 68 69 6c 69 61 63 73 |in..hemo|philiacs|
|00005790| 2e 0d 0a 0d 0a 50 6f 73 | 74 2d 43 6f 6d 6d 65 6e |.....Pos|t-Commen|
|000057a0| 74 0d 0a 0d 0a 20 20 20 | 20 20 49 74 20 68 61 73 |t.... | It has|
|000057b0| 20 62 65 65 6e 20 73 68 | 6f 77 6e 20 74 68 61 74 | been sh|own that|
|000057c0| 20 61 6c 6c 20 62 6c 6f | 6f 64 20 63 6f 6d 70 6f | all blo|od compo|
|000057d0| 6e 65 6e 74 73 20 66 72 | 6f 6d 20 48 49 56 2d 69 |nents fr|om HIV-i|
|000057e0| 6e 66 65 63 74 65 64 20 | 64 6f 6e 6f 72 73 20 63 |nfected |donors c|
|000057f0| 61 6e 0d 0a 74 72 61 6e | 73 6d 69 74 20 74 68 65 |an..tran|smit the|
|00005800| 20 76 69 72 75 73 20 28 | 73 65 65 20 74 68 65 20 | virus (|see the |
|00005810| 31 39 38 38 20 59 45 41 | 52 20 42 4f 4f 4b 20 4f |1988 YEA|R BOOK O|
|00005820| 46 20 46 41 4d 49 4c 59 | 20 50 52 41 43 54 49 43 |F FAMILY| PRACTIC|
|00005830| 45 2c 20 70 70 20 31 34 | 35 2d 31 34 36 29 2e 0d |E, pp 14|5-146)..|
|00005840| 0a 41 6c 74 68 6f 75 67 | 68 20 6f 6e 65 20 6d 61 |.Althoug|h one ma|
|00005850| 79 20 6e 6f 74 20 62 65 | 20 61 62 6c 65 20 74 6f |y not be| able to|
|00005860| 20 65 71 75 61 74 65 20 | 74 72 61 6e 73 66 75 73 | equate |transfus|
|00005870| 69 6f 6e 2d 61 73 73 6f | 63 69 61 74 65 64 20 48 |ion-asso|ciated H|
|00005880| 49 56 20 69 6e 66 65 63 | 74 69 6f 6e 0d 0a 77 69 |IV infec|tion..wi|
|00005890| 74 68 20 74 68 65 20 6d | 6f 72 65 20 63 6f 6d 6d |th the m|ore comm|
|000058a0| 6f 6e 20 6d 6f 64 65 73 | 2c 20 74 68 65 20 64 61 |on modes|, the da|
|000058b0| 74 61 20 61 72 65 20 6e | 6f 6e 65 74 68 65 6c 65 |ta are n|onethele|
|000058c0| 73 73 20 68 65 6c 70 66 | 75 6c 3b 20 35 30 25 20 |ss helpf|ul; 50% |
|000058d0| 6f 66 0d 0a 72 65 63 69 | 70 69 65 6e 74 73 20 6f |of..reci|pients o|
|000058e0| 66 20 48 49 56 2d 69 6e | 66 65 63 74 65 64 20 62 |f HIV-in|fected b|
|000058f0| 6c 6f 6f 64 20 63 6f 6d | 70 6f 6e 65 6e 74 73 20 |lood com|ponents |
|00005900| 77 69 6c 6c 20 68 61 76 | 65 20 73 6f 6d 65 20 73 |will hav|e some s|
|00005910| 79 6d 70 74 6f 6d 20 6f | 66 20 48 49 56 0d 0a 69 |ymptom o|f HIV..i|
|00005920| 6e 66 65 63 74 69 6f 6e | 20 77 69 74 68 69 6e 20 |nfection| within |
|00005930| 35 20 79 65 61 72 73 2e | 20 20 54 68 69 73 20 73 |5 years.| This s|
|00005940| 74 75 64 79 2c 20 61 6e | 64 20 61 20 72 65 63 65 |tudy, an|d a rece|
|00005950| 6e 74 20 72 65 70 6f 72 | 74 20 62 79 20 47 6f 65 |nt repor|t by Goe|
|00005960| 64 65 72 74 20 61 6e 64 | 0d 0a 63 6f 6c 6c 65 61 |dert and|..collea|
|00005970| 67 75 65 73 20 28 31 29 | 2c 20 64 65 6d 6f 6e 73 |gues (1)|, demons|
|00005980| 74 72 61 74 65 20 61 20 | 73 74 72 69 6b 69 6e 67 |trate a |striking|
|00005990| 20 61 67 65 2d 72 65 6c | 61 74 65 64 20 72 61 74 | age-rel|ated rat|
|000059a0| 65 20 6f 66 20 70 72 6f | 67 72 65 73 73 69 6f 6e |e of pro|gression|
|000059b0| 20 74 6f 20 41 49 44 53 | 0d 0a 66 6f 6c 6c 6f 77 | to AIDS|..follow|
|000059c0| 69 6e 67 20 48 49 56 20 | 69 6e 66 65 63 74 69 6f |ing HIV |infectio|
|000059d0| 6e 2e 20 20 57 69 74 68 | 69 6e 20 38 20 79 65 61 |n. With|in 8 yea|
|000059e0| 72 73 20 6f 66 20 61 63 | 71 75 69 72 69 6e 67 20 |rs of ac|quiring |
|000059f0| 74 68 65 20 69 6e 66 65 | 63 74 69 6f 6e 2c 20 41 |the infe|ction, A|
|00005a00| 49 44 53 20 77 69 6c 6c | 0d 0a 62 65 20 64 69 61 |IDS will|..be dia|
|00005a10| 67 6e 6f 73 65 64 20 69 | 6e 20 72 6f 75 67 68 6c |gnosed i|n roughl|
|00005a20| 79 20 31 30 25 20 6f 66 | 20 74 68 6f 73 65 20 61 |y 10% of| those a|
|00005a30| 67 65 64 20 31 2d 31 37 | 20 79 65 61 72 73 2c 20 |ged 1-17| years, |
|00005a40| 69 6e 20 32 35 25 20 6f | 66 20 74 68 6f 73 65 20 |in 25% o|f those |
|00005a50| 61 67 65 64 0d 0a 31 38 | 2d 33 34 20 79 65 61 72 |aged..18|-34 year|
|00005a60| 73 2c 20 61 6e 64 20 69 | 6e 20 6e 65 61 72 6c 79 |s, and i|n nearly|
|00005a70| 20 35 30 25 20 6f 66 20 | 74 68 6f 73 65 20 61 67 | 50% of |those ag|
|00005a80| 65 64 20 33 35 2d 37 30 | 20 79 65 61 72 73 2e 2d |ed 35-70| years.-|
|00005a90| 2d 4a 2e 47 2e 20 50 72 | 69 63 68 61 72 64 2c 0d |-J.G. Pr|ichard,.|
|00005aa0| 0a 4d 2e 44 2e 2c 20 4d | 2e 48 53 0d 0a 24 55 6e |.M.D., M|.HS..$Un|
|00005ab0| 69 71 75 65 5f 49 44 7b | 59 52 42 31 30 35 30 36 |ique_ID{|YRB10506|
|00005ac0| 7d 0d 0a 24 54 69 74 6c | 65 7b 54 72 61 6e 73 6d |}..$Titl|e{Transm|
|00005ad0| 69 73 73 69 6f 6e 20 6f | 66 20 52 65 74 72 6f 76 |ission o|f Retrov|
|00005ae0| 69 72 75 73 65 73 20 62 | 79 20 54 72 61 6e 73 66 |iruses b|y Transf|
|00005af0| 75 73 69 6f 6e 20 6f 66 | 20 53 63 72 65 65 6e 65 |usion of| Screene|
|00005b00| 64 20 42 6c 6f 6f 64 20 | 69 6e 20 50 61 74 69 65 |d Blood |in Patie|
|00005b10| 6e 74 73 20 55 6e 64 65 | 72 67 6f 69 6e 67 20 43 |nts Unde|rgoing C|
|00005b20| 61 72 64 69 61 63 20 53 | 75 72 67 65 72 79 7d 0d |ardiac S|urgery}.|
|00005b30| 0a 24 41 75 74 68 6f 72 | 7b 43 6f 68 65 6e 2c 20 |.$Author|{Cohen, |
|00005b40| 4e 44 0d 0a 4d 75 6e 6f | 7a 2c 20 41 0d 0a 52 65 |ND..Muno|z, A..Re|
|00005b50| 69 74 7a 2c 20 42 41 0d | 0a 4e 65 73 73 2c 20 50 |itz, BA.|.Ness, P|
|00005b60| 4b 0d 0a 46 72 61 7a 69 | 65 72 2c 20 4f 48 0d 0a |K..Frazi|er, OH..|
|00005b70| 59 61 77 6e 2c 20 44 48 | 0d 0a 4c 65 65 2c 20 48 |Yawn, DH|..Lee, H|
|00005b80| 0d 0a 42 6c 61 74 74 6e | 65 72 2c 20 57 0d 0a 44 |..Blattn|er, W..D|
|00005b90| 6f 6e 61 68 75 65 2c 20 | 4a 47 0d 0a 4e 65 6c 73 |onahue, |JG..Nels|
|00005ba0| 6f 6e 2c 20 4b 45 0d 0a | 50 6f 6c 6b 2c 20 42 46 |on, KE..|Polk, BF|
|00005bb0| 7d 0d 0a 24 41 66 66 69 | 6c 69 61 74 69 6f 6e 7b |}..$Affi|liation{|
|00005bc0| 54 65 78 61 73 20 41 26 | 4d 20 43 6f 6c 6c 65 67 |Texas A&|M Colleg|
|00005bd0| 65 20 6f 66 20 56 65 74 | 65 72 69 6e 61 72 79 20 |e of Vet|erinary |
|00005be0| 4d 65 64 69 63 69 6e 65 | 2c 20 43 6f 6c 6c 65 67 |Medicine|, Colleg|
|00005bf0| 65 20 53 74 61 74 69 6f | 6e 3b 20 4a 6f 68 6e 73 |e Statio|n; Johns|
|00005c00| 20 48 6f 70 6b 69 6e 73 | 20 55 6e 69 76 3b 20 53 | Hopkins| Univ; S|
|00005c10| 74 20 4c 75 6b 65 27 73 | 20 45 70 69 73 63 6f 70 |t Luke's| Episcop|
|00005c20| 61 6c 20 48 6f 73 70 2c | 20 48 6f 75 73 74 6f 6e |al Hosp,| Houston|
|00005c30| 3b 20 42 61 79 6c 6f 72 | 20 43 6f 6c 6c 65 67 65 |; Baylor| College|
|00005c40| 20 6f 66 20 4d 65 64 69 | 63 69 6e 65 2c 20 48 6f | of Medi|cine, Ho|
|00005c50| 75 73 74 6f 6e 3b 20 41 | 62 62 6f 74 74 20 4c 61 |uston; A|bbott La|
|00005c60| 62 73 2c 20 4e 20 43 68 | 69 63 61 67 6f 3b 20 65 |bs, N Ch|icago; e|
|00005c70| 74 20 61 6c 7d 0d 0a 24 | 4a 6f 75 72 6e 61 6c 7b |t al}..$|Journal{|
|00005c80| 4e 20 45 6e 67 6c 20 4a | 20 4d 65 64 7d 0d 0a 24 |N Engl J| Med}..$|
|00005c90| 56 6f 6c 75 6d 65 7b 33 | 32 30 7d 0d 0a 24 50 61 |Volume{3|20}..$Pa|
|00005ca0| 67 65 7b 31 31 37 32 2d | 31 31 37 36 7d 0d 0a 24 |ge{1172-|1176}..$|
|00005cb0| 44 61 74 65 7b 4d 61 79 | 20 34 2c 20 31 39 38 39 |Date{May| 4, 1989|
|00005cc0| 7d 0d 0a 24 59 42 56 6f | 6c 7b 31 39 39 30 20 59 |}..$YBVo|l{1990 Y|
|00005cd0| 65 61 72 20 42 6f 6f 6b | 20 6f 66 20 46 61 6d 69 |ear Book| of Fami|
|00005ce0| 6c 79 20 50 72 61 63 74 | 69 63 65 7d 0d 0a 24 43 |ly Pract|ice}..$C|
|00005cf0| 68 61 70 74 65 72 7b 31 | 2d 37 7d 0d 0a 24 59 42 |hapter{1|-7}..$YB|
|00005d00| 45 64 69 74 6f 72 7b 44 | 72 73 2e 20 52 61 6b 65 |Editor{D|rs. Rake|
|00005d10| 6c 2c 20 41 76 61 6e 74 | 2c 20 44 72 69 73 63 6f |l, Avant|, Drisco|
|00005d20| 6c 6c 2c 20 50 72 69 63 | 68 61 72 64 2c 20 61 6e |ll, Pric|hard, an|
|00005d30| 64 20 53 6d 69 74 68 7d | 0d 0a 24 54 61 62 6c 65 |d Smith}|..$Table|
|00005d40| 7b 7d 0d 0a 24 43 6f 6d | 6d 65 6e 74 61 74 6f 72 |{}..$Com|mentator|
|00005d50| 7b 4a 2e 47 2e 20 50 72 | 69 63 68 61 72 64 2c 20 |{J.G. Pr|ichard, |
|00005d60| 4d 2e 44 2e 2c 20 4d 2e | 48 53 7d 0d 0a 0d 0a 43 |M.D., M.|HS}....C|
|00005d70| 6f 70 79 72 69 67 68 74 | 20 28 63 29 20 59 65 61 |opyright| (c) Yea|
|00005d80| 72 62 6f 6f 6b 20 4d 65 | 64 69 63 61 6c 20 50 75 |rbook Me|dical Pu|
|00005d90| 62 6c 69 73 68 65 72 73 | 2c 20 49 6e 63 2e 2c 20 |blishers|, Inc., |
|00005da0| 31 39 39 30 0d 0a 0d 0a | 31 39 39 30 20 59 65 61 |1990....|1990 Yea|
|00005db0| 72 20 42 6f 6f 6b 20 6f | 66 20 46 61 6d 69 6c 79 |r Book o|f Family|
|00005dc0| 20 50 72 61 63 74 69 63 | 65 20 28 52 29 0d 0a 0d | Practic|e (R)...|
|00005dd0| 0a 43 68 61 70 74 65 72 | 20 31 2d 2d 49 6e 66 65 |.Chapter| 1--Infe|
|00005de0| 63 74 69 6f 75 73 20 44 | 69 73 65 61 73 65 0d 0a |ctious D|isease..|
|00005df0| 0d 0a 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |..------|--------|
|00005e00| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005e10| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005e20| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005e30| 2d 2d 2d 2d 2d 2d 2d 2d | 2d 2d 2d 2d 2d 2d 2d 2d |--------|--------|
|00005e40| 0d 0a 54 72 61 6e 73 6d | 69 73 73 69 6f 6e 20 6f |..Transm|ission o|
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+--------+-------------------------+-------------------------+--------+--------+
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